Month: November 2021

An article Photoinduced Copper-Catalyzed Asymmetric Decarboxylative Alkynylation with Terminal Alkynes WOS:000561037300001 published article about ALIPHATIC CARBOXYLIC-ACIDS; CROSS-COUPLING REACTIONS; REDOX-ACTIVE ESTERS; REGIOSELECTIVE SYNTHESIS; PHOTOREDOX; LIGHT; ARYLATION; STRATEGY; HALIDES in [Xia, Hai-Dong; Dong, Xiao-Yang; Fang, Jia-Heng; Du, Xuan-Yi; Wang, Li-Lei; Liu, Xin-Yuan] Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518055, Peoples R China; [Xia, Hai-Dong; Dong, Xiao-Yang; Fang, Jia-Heng; Du, Xuan-Yi; Wang, Li-Lei; Liu, Xin-Yuan] Southern Univ Sci & Technol, Dept Chem, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Peoples R China; [Li, Zhong-Liang; Gu, Qiang-Shuai] Southern Univ Sci & Technol, Acad Adv Interdisciplinary Studies, Shenzhen 518055, Peoples R China; [Li, Zhong-Liang; Gu, Qiang-Shuai] Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China in 2020, Cited 88. Quality Control of 2-Phenylbutanoic acid. The Name is 2-Phenylbutanoic acid. Through research, I have a further understanding and discovery of 90-27-7

We describe a photoinduced copper-catalyzed asymmetric radical decarboxylative alkynylation of bench-stable N-hydroxyphthalimide(NHP)-type esters of racemic alkyl carboxylic acids with terminal alkynes, which provides a flexible platform for the construction of chiral C(sp(3))-C(sp) bonds. Critical to the success of this process are not only the use of the copper catalyst as a dual photo- and cross-coupling catalyst but also tuning of the NHP-type esters to inhibit the facile homodimerization of the alkyl radical and terminal alkyne, respectively. Owing to the use of stable and easily available NHP-type esters, the reaction features a broader substrate scope compared with reactions using the alkyl halide counterparts, covering (hetero)benzyl-, allyl-, and aminocarbonyl-substituted carboxylic acid derivatives, and (hetero)aryl and alkyl as well as silyl alkynes, thus providing a vital complementary approach to the previously reported method.

Welcome to talk about 90-27-7, If you have any questions, you can contact Xia, HD; Li, ZL; Gu, QS; Dong, XY; Fang, JH; Du, XY; Wang, LL; Liu, XY or send Email.. Quality Control of 2-Phenylbutanoic acid

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics

An article Boron-Catalyzed alpha-Amination of Carboxylic Acids WOS:000487577200058 published article about ELECTROPHILIC AMINATION; ASYMMETRIC-SYNTHESIS; ENANTIOSELECTIVE AMINATION; DERIVATIVES; ACETALS; ESTERS; CYANOACETATES; CONSTRUCTION; COMPLEXES; STRATEGY in [Sawamura, Masaya; Shimizu, Yohei] Hokkaido Univ, Inst Chem React Design & Discovery WPI ICReDD, Kita Ku, Kita 21 Nishi 10, Sapporo, Hokkaido 0010021, Japan; [Morisawa, Takuto; Sawamura, Masaya; Shimizu, Yohei] Hokkaido Univ, Fac Sci, Dept Chem, Kita Ku, Kita 10 Nishi 8, Sapporo, Hokkaido 0600810, Japan in 2019, Cited 45. Product Details of 90-27-7. The Name is 2-Phenylbutanoic acid. Through research, I have a further understanding and discovery of 90-27-7

A boron-catalyzed alpha-amination of simple carboxylic acids was developed. Catalytically generated boron enolates of carboxylic acids reacted with an electrophilic aminating reagent, diisopropylazodicarboxylate, to provide amino acid derivatives. The catalysis afforded not only alpha-monosubstituted glycine derivatives but also alpha,alpha-disubstituted derivatives. The resulting alpha-aminocarboxylic acid was easily converted to carboxylic acid derivatives. Extension to a catalytic asymmetric variant was possible by introducing a chiral ligand on the boron catalyst.

Welcome to talk about 90-27-7, If you have any questions, you can contact Morisawa, T; Sawamura, M; Shimizu, Y or send Email.. Product Details of 90-27-7

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics

In 2020 J AM CHEM SOC published article about DIASTEREOSELECTIVE SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; ESTERS; BOAT in [Fulton, Tyler J.; Cusumano, Alexander Q.; Alexy, Eric J.; Du, Yun E.; Stoltz, Brian M.] CALTECH, Warren & Katharine Schlinger Lab Chem & Chem Engn, Div Chem & Chem Engn, Pasadena, CA 91125 USA; [Zhang, Haiming] Genentech Inc, Small Mol Proc Chem, San Francisco, CA 94080 USA; [Houk, K. N.] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA in 2020, Cited 35. The Name is 2-Phenylbutanoic acid. Through research, I have a further understanding and discovery of 90-27-7. Recommanded Product: 90-27-7

A dual experimental/theoretical investigation of the Ireland-Claisen rearrangement of tetrasubstituted alpha-phthalimido ester enolates to afford alpha-tetrasubstituted, beta-trisubstituted alpha-amino acids (generally >20:1 dr) is described. For trans allylic olefins, the Z- and E-enol ethers proceed through chair and boat transition states, respectively. For cis allylic olefins, the trend is reversed. As a result, the diastereochemical outcome of the reaction is preserved regardless of the geometry of the enolate or the accompanying allylic olefin. We term this unique convergence of all possible olefin isomers global diastereoconvergence. This reaction manifold circumvents limitations in present-day technologies for the stereoselective enolization of alpha,alpha-disubstituted allyl esters. Density functional theory paired with state-of-the-art local coupled-cluster theory (DLPNO-CCSD(T)) was employed for the accurate determination of quantum mechanical energies.

Welcome to talk about 90-27-7, If you have any questions, you can contact Fulton, TJ; Cusumano, AQ; Alexy, EJ; Du, YE; Zhang, HM; Houk, KN; Stoltz, BM or send Email.. Recommanded Product: 90-27-7

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics

Recently I am researching about SP(3) C-H; CARBOXYLIC-ACIDS; COUPLING CDC; ESTERIFICATION; BOND; ACTIVATION; ALDEHYDES; C(SP(3))-H; COMPLEXES; ALKYLBENZENES, Saw an article supported by the Council of Scientific & Industrial Research (CSIR), New DelhiCouncil of Scientific & Industrial Research (CSIR) – India [01(5234)/15]; Department of Science & Technology (DST)Department of Science & Technology (India) [YSS/2015/001552]; CSIRCouncil of Scientific & Industrial Research (CSIR) – India; UGCUniversity Grants Commission, India; IIESTS. Published in ELSEVIER SCIENCE SA in LAUSANNE ,Authors: Mondal, R; Chakraborty, G; van Vliet, KM; van Leest, NP; de Bruin, B; Paul, ND. The CAS is 90-27-7. Through research, I have a further understanding and discovery of 2-Phenylbutanoic acid. Application In Synthesis of 2-Phenylbutanoic acid

Herein, we report a general, efficient and solvent-free method for the one-pot synthesis of allylic esters via dehydrogenation of unactivated alkanes and subsequent oxidative cross coupling with different substituted carboxylic acids. A simple, well defined and air stable Cu(II)-complex, [Cu(MeTAA)], featuring a tetraazamacrocyclic ligand (tetramethyltetraaza[14]annulene (MeTAA)) is used as the catalyst. A wide variety substituted allylic esters were synthesized in high yields starting from readily available starting materials. Control reactions were carried out to understand the reaction sequence and the plausible mechanism.

Welcome to talk about 90-27-7, If you have any questions, you can contact Mondal, R; Chakraborty, G; van Vliet, KM; van Leest, NP; de Bruin, B; Paul, ND or send Email.. Application In Synthesis of 2-Phenylbutanoic acid

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics

An article Modeling and optimization of lipase-catalyzed hydrolysis for production of (S)-2-phenylbutyric acid enhanced by hydroxyethyl-beta-cyclodextrin WOS:000474502600011 published article about CANDIDA-ANTARCTICA LIPASE; ENANTIOSELECTIVE HYDROLYSIS; ETHYL-ESTER; ENZYME-ACTIVITY; REACTION SYSTEM; RESOLUTION; IMMOBILIZATION; ESTERIFICATION; SEPARATION; INDOBUFEN in [Zhang, Panliang; Cheng, Qing; Xu, Weifeng; Tang, Kewen] Hunan Inst Sci & Technol, Dept Chem & Chem Engn, Yueyang 414000, Hunan, Peoples R China in 2019, Cited 44. The Name is 2-Phenylbutanoic acid. Through research, I have a further understanding and discovery of 90-27-7. Application In Synthesis of 2-Phenylbutanoic acid

An efficient reactive system was established to produce (S)-2-phenylbutyric acid (2-PBA) through the enzymatic enantioselective hydrolysis of 2-phenylbutyrate ester (2-PBAE) in aqueous medium. Lipase CALA from Canadian antarctica and hexyl 2-phenylbutyrate (2-PBAHE) were identified upon screening as the best enzyme and substrate, respectively. Adding hydroxyethyl-beta-cyclodextrin (HE-beta-CD) to improve the solubility of the substrate resulted in a 1.5 times increase in substrate conversion while retaining a high enantioselectivity compared with that when HE-beta-CD was not added. The effects of lipase concentration, substrate concentration and HE-beta-CD concentration, temperature, pH, and reaction time on enantiomeric excess and conversion rate were investigated, and the optimal conditions were identified using response surface methodology (RSM). Under the optimal conditions, namely 50 mg/mL lipase CALA, 30 mmol/L substrate, 60 mmol/L HE-beta-CD, pH of 6.5, temperature of 83 degrees C and reaction time of 18 h, the enantiomeric excess and overall conversion rate were 96.05% and 27.28%, respectively. This work provides an efficient alternative method for improving the conversion of aromatic ester substrates by including beta-cyclodextrin in an aqueous hydrolysis reaction system.

Welcome to talk about 90-27-7, If you have any questions, you can contact Zhang, PL; Cheng, Q; Xu, WF; Tang, KW or send Email.. Application In Synthesis of 2-Phenylbutanoic acid

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics

An article A Mild Method for Access to alpha-Substituted Dithiomalonates through C-Thiocarbonylation of Thioester: Synthesis of Mesoionic Insecticides WOS:000655568100001 published article about CARBON BOND FORMATION; CLAISEN CONDENSATION; PRACTICAL SYNTHESIS; SOFT ENOLIZATION; MICHAEL ADDITION; ACID; BIOSYNTHESIS; DISCOVERY; KETONES; TRIFLUMEZOPYRIM in [Yang, Xinyue; Ma, Yanrong; Di, Huiming; Wang, Xiaochen; Jin, Hui; Zhang, Lixin] Shenyang Univ Chem Technol, Inst Funct Mol, Shenyang 110142, Peoples R China; [Yang, Xinyue; Ma, Yanrong; Di, Huiming; Wang, Xiaochen; Jin, Hui; Zhang, Lixin] Natl Local Joint Engn Lab Dev Boron & Magnesium R, Shenyang 110142, Peoples R China; [Yang, Xinyue; Ma, Yanrong; Di, Huiming; Wang, Xiaochen; Jin, Hui; Zhang, Lixin] Liaoning Prov Key Lab Green Funct Mol Design & De, Shenyang 110142, Peoples R China; [Ryu, Do Hyun] Sungkyunkwan Univ, Dept Chem, Suwon 440746, South Korea in 2021, Cited 53. The Name is 2-Phenylbutanoic acid. Through research, I have a further understanding and discovery of 90-27-7. Name: 2-Phenylbutanoic acid

An efficient method for targeting a variety of symmetrical and asymmetrical alpha-substituted dithiomalonates (DTMs) is described, utilizing 1H-imidazole-1-carbothioates as reactive acylating agents and MgBr2 center dot OEt2/DBU or LiHMDS for soft or hard enolization conditions of thioesters, respectively. The utility of this methodology was demonstrated through the synthesis of the pyridopyrimidine mesoionic insecticides: triflumezopyrim and dicloromezotiaz.

Welcome to talk about 90-27-7, If you have any questions, you can contact Yang, XY; Ma, YR; Di, HM; Wang, XC; Jin, H; Ryu, DH; Zhang, LX or send Email.. Name: 2-Phenylbutanoic acid

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics

Recommanded Product: 90-27-7. Authors Duan, SG; Hong, K; Tang, M; Tang, J; Liu, LX; Gao, GF; Shen, ZJ; Zhang, XM; Yi, Y in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Duan, Sheng-Guang; Hong, Kun; Tang, Ming; Tang, Jing; Liu, Lun-Xian; Zhang, Xi-Min; Yi, Yin] Guizhou Normal Univ, Sch Life Sci, Key Lab Natl Forestry & Grassland Adm Biodivers C, Key Lab Plant Physiol & Dev Regulat, Guiyang 550001, Guizhou, Peoples R China; [Gao, Gui-Feng] Chinese Acad Sci, Inst Soil Sci, State Key Lab Soil & Sustainable Agr, Nanjing 210008, Peoples R China; [Shen, Zhi-Jun] Xiamen Univ, Coll Environm & Ecol, Key Lab Subtrop Wetland Ecosyst Res, Minist Educ, Xiamen 361005, Fujian, Peoples R China in 2021, Cited 56. The Name is 2-Phenylbutanoic acid. Through research, I have a further understanding and discovery of 90-27-7

Petal blight caused by fungi is among the most destructive diseases of Rhododendron, especially Rhododendron agastum. Nonetheless, the metabolite changes that occur during petal blight are unknown. We used untargeted gas chromatography time-of-flight mass spectrometry (GC-TOF-MS) and ultra-high performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry (UHPLC-QTOF-MS/MS) to compare the metabolite profiles of healthy and petal blight R. agastum flowers. Using GC-TOF-MS, 571 peaks were extracted, of which 189 metabolites were tentatively identified. On the other hand, 364 and 277 metabolites were tentatively identified in the positive and negative ionization modes of the UHPLC-QTOF-MS/MS, respectively. Principal component analysis (PCA) and orthogonal projections to latent structures-discriminant analysis (OPLS-DA) were able to clearly discriminate between healthy and petal blight flowers. Differentially abundant metabolites were primarily enriched in the biosynthesis of specialized metabolites. 17 accumulated specialized metabolites in petal blight flowers have been reported to have antifungal activity, and literature indicates that 9 of them are unique to plants. 3 metabolites (chlorogenic acid, medicarpin, and apigenin) are reportedly involved in resistance to blight caused by pathogens. We therefore speculate that the accumulation of chlorogenic acid, medicarpin, and apigenin may be involved in the resistance to petal blight. Our results suggest that these metabolites may be used as candidate biocontrol agents for the control fungal petal blight in Rhododendron.

Welcome to talk about 90-27-7, If you have any questions, you can contact Duan, SG; Hong, K; Tang, M; Tang, J; Liu, LX; Gao, GF; Shen, ZJ; Zhang, XM; Yi, Y or send Email.. Recommanded Product: 90-27-7

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics

HPLC of Formula: C10H12O2. Mandrelli, F; Blond, A; James, T; Kim, H; List, B in [Mandrelli, Francesca; Blond, Aurelie; James, Thomas; Kim, Hyejin; List, Benjamin] Max Planck Inst Kohlenforsch, Kaiser Wilhelm Pl 1, D-45470 Mulheim, Germany published Deracemizing alpha-Branched Carboxylic Acids by Catalytic Asymmetric Protonation of Bis-Silyl Ketene Acetals with Water or Methanol in 2019, Cited 52. The Name is 2-Phenylbutanoic acid. Through research, I have a further understanding and discovery of 90-27-7.

We report a highly enantioselective catalytic protonation of bis-silyl ketene acetals. Our method delivers alpha-branched carboxylic acids, including nonsteroidal anti-inflammatory arylpropionic acids such as Ibuprofen, in high enantiomeric purity and high yields. The process can be incorporated in an overall deracemization of alpha-branched carboxylic acids, involving a double deprotonation and silylation followed by the catalytic asymmetric protonation.

Welcome to talk about 90-27-7, If you have any questions, you can contact Mandrelli, F; Blond, A; James, T; Kim, H; List, B or send Email.. HPLC of Formula: C10H12O2

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics

SDS of cas: 90-27-7. In 2020 ORGANOMETALLICS published article about DENSITY-FUNCTIONAL THEORY; CO2 INSERTION; CARBON; ALKENES; DFT; HYDROCARBOXYLATION; THERMOCHEMISTRY in [Obst, Marc F.; Hopmann, Kathrin H.] UiT Arctic Univ Norway, Hylleraas Ctr Quantum Mol Sci, Dept Chem, N-9037 Tromso, Norway; [Gevorgyan, Ashot; Bayer, Annette] UiT Arctic Univ Norway, Dept Chem, N-9037 Tromso, Norway in 2020, Cited 38. The Name is 2-Phenylbutanoic acid. Through research, I have a further understanding and discovery of 90-27-7.

The copper-NHC-catalyzed carboxylation of organo-boranes with CO2 was investigated using computational and experimental methods. The DFT and DLPNO-CCSD(T) results indicate that nonbenzylic substrates are converted via an inner-sphere carboxylation of an organocopper intermediate, whereas benzylic substrates may simultaneously proceed along both inner- and outer-sphere CO2 insertion pathways. Interestingly, the computations predict that two conceptually different carboxylation mechanisms are possible for benzylic organoboranes, one being copper-catalyzed and one being mediated by the reaction additive CsF. Our experimental evaluation of the computed reactions confirms that carboxylation of nonbenzylic substrates requires copper catalysis, whereas benzylic substrates can be carboxylated with and without copper.

Welcome to talk about 90-27-7, If you have any questions, you can contact Obst, MF; Gevorgyan, A; Bayer, A; Hopmann, KH or send Email.. SDS of cas: 90-27-7

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics

Recently I am researching about B(C6F5)(3)-CATALYZED HYDROSILYLATION; CARBONYL; MECHANISM; SILANES, Saw an article supported by the Berlin Graduate School of Natural Sciences and Engineering; Projekt DEAL. Name: 2-Phenylbutanoic acid. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Roy, A; Oestreich, M. The CAS is 90-27-7. Through research, I have a further understanding and discovery of 2-Phenylbutanoic acid

Little-explored hydrosilylation of ketenes promoted by main-group catalysts is reported. The boron Lewis acid tris(pentafluorophenyl)borane accelerates the slow uncatalyzed reaction of ketenes and hydrosilanes, thereby providing a convenient access to the new class of beta,beta-di- and beta-monoaryl-substituted aldehyde-derived silyl enol ethers. Yields are moderate to high, and Z configuration is preferred. The corresponding silyl bis-enol ethers are also available when using dihydrosilanes. The related trityl-cation-initiated hydrosilylation involving self-regeneration of silylium ions is far less effective.

Welcome to talk about 90-27-7, If you have any questions, you can contact Roy, A; Oestreich, M or send Email.. Name: 2-Phenylbutanoic acid

Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics