New discoveries in chemical research and development in 2021.As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 6009-70-7, Name is Ammonium oxalate monohydrate, SMILES is O=C([O-])C([O-])=O.[H]O[H].[NH4+].[NH4+], in an article , author is Guo, Sheng, once mentioned of 6009-70-7, Computed Properties of https://www.ambeed.com/products/6009-70-7.html.
A Cu-catalyzed enantioselective hydroamination of alpha,beta-unsaturated carbonyl compounds for the synthesis of beta-amino acid derivatives was achieved through ligand-controlled reversal of the hydrocupration regioselectivity. While the hydrocupration of alpha,beta-unsaturated carbonyl compounds to form alpha-cuprated species has been extensively investigated, we report herein that, in the presence of an appropriate ancillary chiral ligand, the opposite regiochemistry can be observed for cinnamic acid derivatives, leading to the delivery of the copper to the beta-position. This copper can react with an electrophilic aminating reagent, 1,2-benzisoxazole, to provide enantioenriched beta-amino acid derivatives, which are important building blocks for the synthesis of natural products and bioactive small molecules.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 6009-70-7. Computed Properties of https://www.ambeed.com/products/6009-70-7.html.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics