The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Furoic hydrazide( cas:3326-71-4 ) is researched.Computed Properties of C5H6N2O2.Maurya, Mannar R.; Jangra, Nancy; Avecilla, Fernando; Correia, Isabel published the article 《4,6-Diacetyl Resorcinol Based Vanadium(V) Complexes: Reactivity and Catalytic Applications》 about this compound( cas:3326-71-4 ) in European Journal of Inorganic Chemistry. Keywords: vanadium acetylresorcinol hydrazide complex preparation oxidation catalyst thermal stability; electrochem vanadium acetylresorcinol hydrazide complex; crystal structure vanadium acetylresorcinol hydrazide complex. Let’s learn more about this compound (cas:3326-71-4).
Four ONO donor ligands are isolated from the condensation of 4,6-diacetyl resorcinol with isonicotinoyl hydrazide (H2dar-inh, I), nicotinoyl hydrazide (H2dar-nah, II), benzoyl hydrazide (H2dar-bhz, III), and 2-furoyl hydrazide (H2dar-fah, IV) on refluxing in MeOH. The reaction of in situ generated aqueous K[H2VVO4] with ligands I-IV at neutral pH gives complexes [K(H2O)2][VO2(dar-inh)] (1), [K(H2O)2][VO2(dar-nah)] (2), [K(H2O)2][VO2(dar-bhz)] (3), and [K(H2O)2][VO2(dar-fah)] (4), resp. The reaction of [VIVO(acac)2] (acac = acetylacetonato) with these ligands (I-IV) under aerobic conditions in methanol yields oxidomethoxidovanadium(V) complexes [VO(OMe)(MeOH)(dar-inh)] (5), [VO(OMe)(MeOH)(dar-nah)] (6), [VO(OMe)(MeOH)(dar-bhz)] (7), and [VO(OMe)(MeOH)(dar-fah)] (8). All the isolated complexes are characterized by elemental, thermal, electrochem., and spectroscopic techniques [FTIR, UV/Vis, NMR (1H, 13C and 51 V NMR)], and single-crystal X-ray diffraction anal. (for 1, 6, 7, and 8). X-ray anal. confirms the coordination of the ligands through Ophenolate, Nazomethine, and Oenolate to the metal center. In the mol. structure of [K(H2O)(EtOH)][VVO2(dar-inh)] (abbreviated as 1a where one mol. of water is replaced by EtOH), water mols. act as bridges between two K+ ions and the complex shows a dimeric structure due to the presence of electrostatic interactions between V=O oxygen atoms with K+ ions. These complexes are active catalysts for the oxidative bromination of thymol in the presence of KBr, HClO4, and H2O2 and give 2-bromothymol, 4-bromothymol, and 2,4-dibromothymol as major products. Complexes 1-4 were also tested as catalysts for the epoxidation of various alkenes (namely styrene, cyclohexene, cis-cyclooctene, 1-hexene, 1-octene, cyclohexenone, and trans-stilbene) with H2O2 in the presence of NaHCO3 as promoter, giving the corresponding epoxides selectively.
In addition to the literature in the link below, there is a lot of literature about this compound(2-Furoic hydrazide)Computed Properties of C5H6N2O2, illustrating the importance and wide applicability of this compound(3326-71-4).
Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics