610-09-3 | Page 14 of 23 | Heterocyclic Building Blocks-Benzisoxazole

Fun Route: New Discovery of 610-09-3

Compound(610-09-3)Application of 610-09-3 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-Cyclohexane-1,2-dicarboxylic acid), if you are interested, you can check out my other related articles.

Kim, Eun Young; Park, Hyun Min; Kim, Ha-Yeong; Kim, Jin Hoon; Hyun, Min Young; Lee, Ju Hoon; Kim, Cheal; Kim, Sung-Jin; Kim, Youngmee published the article 《Novel CdII coordination polymers (1-D, 2-D to 3-D) constructed from 1,2-cyclohexanedicarboxylate and various bipyridyl ligands》. Keywords: cadmium cyclohexanedicarboxylate bipyridyl coordination polymer preparation crystal structure luminescence.They researched the compound: cis-Cyclohexane-1,2-dicarboxylic acid( cas:610-09-3 ).Application of 610-09-3. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:610-09-3) here.

Four CdII-(e,a-cis-1,2-chdc) complexes, [Cd(H2O)(1,2-chdc)(2,2′-bpy)] 1, [Cd(1,2-chdc)(bpe)]n 2, [Cd2(1,2-chdc)(4,4′-bpy)2]n 3A, and [Cd(H2O)(1,2-chdc)(4,4′-bpy)2]n·3n(H2O) 3B (1,2-chdc = cis-1,2-cyclohexanedicarboxylate), with different assistant ligands (2,2′-bipyridine (2,2′-bpy), 1,2-bis(4-pyridyl)ethene (bpe), and 4,4′-bipyridine (4,4′-bpy)) were synthesized and their structures were determined Depending on the assistant ligands, the structures and dimensionalities of CdII-(e,a-cis-1,2-chdc) complexes were varied. Two carboxylates in e,a-cis-1,2-chdc coordinate to CdII ions in chelating (η1:η1), bridging (η1:η1:μ2), and chelating/bridging (η2:η1:μ2) modes. Photoluminescence study of the compounds 1 and 2 showed emission of compound 1 was observed at 348 nm, while relatively weak luminescence was displayed at 516 nm for 2. The thermal stabilities of these complexes were also examined

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The important role of 610-09-3

Compound(610-09-3)Synthetic Route of C8H12O4 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-Cyclohexane-1,2-dicarboxylic acid), if you are interested, you can check out my other related articles.

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Mass spectra of carboxylic acids. IV. Carboxyl-carboxyl interaction in some cycloalkane-1,2-dicarboxylic acids and its relation with molecular geometry.Synthetic Route of C8H12O4.

The interaction of the (arboxyl groups in the fragmentation of the mol. ions of trans-cyclohexane-1,2-dicarboxylic acid and cis-cyclobutane-1,2-dicarboxylic acid distinguishes these acids from their cis and trans isomers, resp. This ortho effect is related to the geometrical arrangement of the carboxyl groups in the ground-state mols.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Archives for Chemistry Experiments of 610-09-3

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Stereoisomeric biologically active compounds. I. Some conversions of cis-4-chloro-4-cyclohexene-1,2-dicarboxylic acid, published in 1965, which mentions a compound: 610-09-3, mainly applied to , Synthetic Route of C8H12O4.

cf. Baeyer, Ann. Chem. 258, 215(1890); U.S. 1,967,862, CA 28, 5994. To 10 g. cis-4-chloro-4-cyclohexene-1,2-dicarboxylic acid (I) and 60 ml. H2O, under cooling and stirring, a solution of 21 g. KMnO4 in 650 650 ml. H2O was added over 3 hrs. The cooling and stirring was another 2 hrs. and the mixture left standing overnight, yielding meso-butane-1,2,3,4-tetracarboxylic acid m. 191-2°. I (204.5 g.) and 15 ml. concentrated H2SO4 in 500 ml. absolute MeOH was refluxed for 8 hrs. Dimethyl cis-4-chloro-4-cyclohexene-1,2-dicarboxylate (II), b5 148-50°, d204 1.0553, n20D 1.4935 was obtained in 71.3% yield. II (20 g.) and 18 ml. 85% H2NNH2 was refluxed for 3 hrs. Trans-4-chloro-4-cyclohexene-1,2-dicarboxylic acid dihydrazide (III) m. 222-4° (60% EtOH) was obtained in 69.5% yield. To 30 g. III in 105 ml. 10% HCl and 280 ml. CH2Cl2 at 18-20°, a solution of 20.8 g. NaNO3 in 48.5 ml. H2O was slowly added. The nonaqueous layer was dried, filtered, and treated with 160 ml. absolute EtOH. The CH2Cl2 was evaporated, the mixture refluxed for 2 hrs., 210 ml. 40% NaOH added and steam distilled The distillate was acidified with 10% HCl giving the trans-4-chloro-1,2-diamino-4-cyclohexene-2HCl m. 326-8° in 72.1% yield. III (38 g.) and a solution of 26.6 g. NaOH in 350 ml. H2O was refluxed for 12 hrs. and acidified, giving trans-4-chloro-4-cyclohexene-1,2-dicarboxylic acid (IV) m. 115-17° (H2O) in 89.8% yield. IV (10 g.) was oxidized with KMnO4 as described above, giving the dianhydride of dl-butane-1,2,3,4-tetracarboxylic acid m. 172-3°. A solution of 21 g. IV, 8 g. NaOH and 70 ml. H2O was hydrogenated in an autoclave in the presence of 35 g. Ni on Cr2O3 at 100° and 100 atm. The solution was filtered and acidified giving trans-cyclohexane-1,2-dicarboxylic acid (V) m. 220° (Me2O) in 78.2% yield. I (60 g.) and 23.5 g. NaOH in 200 ml. H2O was hydrogenated as described above giving cis-cyclohexane-1,2-dicarboxylic acid (VI), m. 192°, in 92.1% yield. A mixture of 8 g. VI and 20 ml. concentrated HCl was heated in a sealed tube at 180° for 8-10 hrs. and V, m. 220-1°, was obtained in 88.8% yield.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Some scientific research tips on 610-09-3

Compound(610-09-3)Reference of cis-Cyclohexane-1,2-dicarboxylic acid received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-Cyclohexane-1,2-dicarboxylic acid), if you are interested, you can check out my other related articles.

Thuery, Pierre; Atoini, Youssef; Harrowfield, Jack published the article 《Crown Ethers and Their Alkali Metal Ion Complexes as Assembler Groups in Uranyl-Organic Coordination Polymers with cis-1,3-, cis-1,2-, and trans-1,2-Cyclohexanedicarboxylates》. Keywords: uranyl alkali metal crown ether cyclohexanedicarboxylate polymeric complex preparation; crystal structure uranyl alkali metal crown ether cyclohexanedicarboxylate polymer; luminescence uranyl alkali metal crown ether cyclohexanedicarboxylate polymeric complex.They researched the compound: cis-Cyclohexane-1,2-dicarboxylic acid( cas:610-09-3 ).Reference of cis-Cyclohexane-1,2-dicarboxylic acid. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:610-09-3) here.

Alkali metal cations (Na+, K+) and crown ether mols. (12C4, 15C5, 18C6) were used as addnl. reactants during the hydrothermal synthesis of uranyl ion complexes with cis/trans-1,3-, cis-1,2- and trans-1,2-cyclohexanedicarboxylic acids (c/t-1,3-chdcH2, c-1,2-chdcH2, and t-1,2-chdcH2, resp., the latter as racemic or pure (1R,2R) enantiomer). Oxalate anions generated in situ are present in all the six complexes isolated and crystallog. characterized, [(UO2)2(c-1,3-chdc)2(C2O4)][UO2(H2O)5]·(12C4)·2H2O (1), [(UO2)4Na2(c-1,2-chdc)2(C2O4)3(15C5)2] (2), [(UO2)4K2(c-1,2-chdc)2(C2O4)3(18C6)1.5(H2O)1.5] (3), [(UO2)12K5(R-t-1,2-chdc)4(C2O4)10(18C6)5(OH)(H2O)3]·4H2O (4), [(UO2)12K5(rac-t-1,2-chdc)4(C2O4)10(18C6)5(OH)(H2O)3]·4H2O (5), and [(UO2)8K4(rac-t-1,2-chdc)4(C2O4)6(18C6)3(H2O)2] (6). In complex 1, the [UO2(H2O)5]2+ counterions link the ladderlike uranyl-containing one-dimensional polymers and the uncomplexed crown ether mols. through hydrogen bonds. In all the other complexes, two-dimensional uranyl/chdc/oxalate subunits are formed, with topologies depending on the stoichiometry, in which the 1,2-chdc2- ligands are bound to three uranium atoms, one of them chelated by the two carboxylate groups, and the oxalate ligands are bis-chelating. In complex 2, the Na(15C5)+ cations are bound to one layer through double Na-carboxylate or Na-oxo cis-bonding and they are thus mere decorating groups. In contrast, the quasi-planar K(18C6)+ groups in 3-6, partially affected by disorder, are generally trans-coordinated to two uranyl oxo groups pertaining to different layers, thus uniting the latter into a three-dimensional framework.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

New explortion of 610-09-3

Compound(610-09-3)Quality Control of cis-Cyclohexane-1,2-dicarboxylic acid received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-Cyclohexane-1,2-dicarboxylic acid), if you are interested, you can check out my other related articles.

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Conformation and reactivity. I. Kinetics of the alkaline hydrolysis of the methyl cyclohexanemono- and -dicarboxylate and 4-tert-butylcyclohexanecarboxylates》. Authors are Cavell, E. A. S.; Chapman, N. B.; Johnson, M. D..The article about the compound:cis-Cyclohexane-1,2-dicarboxylic acidcas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O).Quality Control of cis-Cyclohexane-1,2-dicarboxylic acid. Through the article, more information about this compound (cas:610-09-3) is conveyed.

The preparation of pure cis- and trans-4-tert-butylcyclohexanecarboxylic acid and their Me esters was described. Heats and entropies of activation for the alk. hydrolysis of these esters in 1:1 dioxane-H2O, of Me cyclohexanecarboxylate in 1:1 and 1:3 dioxane-H2O, and of all the Me H and di-Me cyclohexanedicarboxylates in 1:3 dioxane-H2O were determined by the methods of Frost and Schwemer (CA 46, 6474h) and of Widequist (CA 46, 9954c) where necessary. Since Me trans-4-tert-butylcyclohexanecarboxylate adopted the diequatorial conformation exclusively, the reactivity in hydrolysis of an equatorial methoxycarbonyl group was characterized, also, with less certainty, that of an axial group, which was hydrolyzed at least 17 times more slowly at 30°. The methoxycarbonyl group was apparently more stable in the equatorial than in the axial conformation. The conformations of the various Me H and di-Me cyclohexanedicarboxylates were discussed in the light of the kinetics of their hydrolyses, and conformational, electrostatic, and primary steric effects in the hydrolyses were elucidated.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Never Underestimate the Influence Of 610-09-3

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis, crystal structures, photoluminescence, and catalytic reactivity of novel coordination polymers (0-D, 1-D, 2-D to 3-D) constructed from cis-1,2-cyclohexanedicarboxylic acid and various bipyridyl ligands, published in 2011, which mentions a compound: 610-09-3, Name is cis-Cyclohexane-1,2-dicarboxylic acid, Molecular C8H12O4, Application of 610-09-3.

Six ZnII-(e,a-cis-1,2-chdc) complexes, [Zn2(1,2-chdc)2(2,2′-bpy)2(H2O)2]·H2O (1), [{Zn2(1,2-chdc)2(H2O)2(μ-bpa)}·4H2O]n (2), [{Zn2(μ-1,2-chdc)2(μ-4,4′-bpy)}·2CH3OH]n (3), [{Zn2(μ-1,2-chdc)2(μ-bpe)}·2H2O]n (4), [[{Zn2(μ-1,2-chdc)2}n-(μ-bpp)2-{Zn2(μ-1,2-hdc)2(H2O)2}]·CH3CN·2H2O]n (5), and [{Zn(μ-dtp)(μ-1,2-chdc)}2·4·5H2O]n (6) (1,2-chdc = 1,2-cyclohexanedicarboxylate), with different assistant ligands (2,2′-bipyridine (2,2′-bpy), 1,2-bis(4-pyridyl)ethane (bpa), 1,2-bis(4-pyridyl)ethylene (bpe), 1,3-bis(4-pyridyl)propane (bpp), and, 4,4′-bipyridine (4,4′-bpy) and 4,4′-dithiodipyridine (dtp)) were synthesized and their structures were determined Depending on the assistant ligands, the structures and dimensionalities of ZnII-(e,a-cis-1,2-chdc) complexes were varied. Two carboxylates in e,a-cis-1,2-chdc coordinate to ZnII ions with (11) or (10) connectivity. Photoluminescence study of the compounds 1-6 showed that emission spectra of compounds 1, 2, 4, and 5 were observed at 343 nm for 1, 419 nm for 2, 507 nm for 4, 396 nm for 5, resp., while no obvious luminescences were displayed for 3 and 6. Compound 1 catalyzed the transesterification reaction of Ph acetate with methanol, with quant. conversion to Me acetate, under the neutral conditions, while compounds 2-6 showed very slow conversions. The thermal stabilities of these complexes were also examined

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Introduction of a new synthetic route about 610-09-3

Here is just a brief introduction to this compound(610-09-3)Category: benzisoxazole, more information about the compound(cis-Cyclohexane-1,2-dicarboxylic acid) is in the article, you can click the link below.

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《The heats of hydration and energy contents of cis- and trans-cyclohexane-1,2-dicarboxylic acids, and their primary ions》. Authors are Wassermann, Albert.The article about the compound:cis-Cyclohexane-1,2-dicarboxylic acidcas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O).Category: benzisoxazole. Through the article, more information about this compound (cas:610-09-3) is conveyed.

The following values were obtained for the cis- and trans-cyclohexane-1,2-dicarboxylic acids and their ions, resp.: heat of combustion, kg.-cal./mole (constant temperature) 931.9, 929.5; heat of solution + first heat of ionization, -7.49, -6.48; energy content of primary anion in dilute solution, kg.-cal./mole 939.4, 936.0; mol. volume at 0° 126.5, 120.4; second heat of ionization +0.30, +0.24. The first ionization constant of the cis acid increases with rise in temperature, while that of the trans decreases. This leads to the conclusion that the trans ion is more hydrated than the cis ion, although the heat of hydration of the undissociated cis is not measurably greater than that of the trans acid.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The effect of the change of synthetic route on the product 610-09-3

Here is just a brief introduction to this compound(610-09-3)Electric Literature of C8H12O4, more information about the compound(cis-Cyclohexane-1,2-dicarboxylic acid) is in the article, you can click the link below.

Electric Literature of C8H12O4. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Neel temperature enhancement by increasing the in-plane magnetic correlation in layered inorganic-organic hybrid materials. Author is Zheng, Yan-Zhen; Xue, Wei; Zheng, Shao-Liang; Tong, Ming-Liang; Chen, Xiao-Ming.

Three inorganic-organic hybrid compounds, [MnII4(trans-1,2-chdc)4(H2O)]·0.25H2O, [MnII2(cis-1,2-chdc)2] and [MnII3(μ3-OH)2(1,2-chedc)2], were hydrothermally synthesized by controlling the conformation of cyclohexane-1,2-dicarboxylate (chdc) and cyclohex-1-ene-1,2-dicarboxylate (chedc), and characterized by x-ray crystallog. and magnetic measurements. These compounds have different infinite inorganic Mn-O layers with an interesting effect of the in-plane magnetic correlation on the Neel temperature

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Derivation of elementary reaction about 610-09-3

Compound(610-09-3)Product Details of 610-09-3 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-Cyclohexane-1,2-dicarboxylic acid), if you are interested, you can check out my other related articles.

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Improved synthesis of cis-Δ4-tetrahydrophthalic anhydride and cis-hexahydrophthalic acid》. Authors are Jenkins, Edward F.; Costello, Edward J..The article about the compound:cis-Cyclohexane-1,2-dicarboxylic acidcas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O).Product Details of 610-09-3. Through the article, more information about this compound (cas:610-09-3) is conveyed.

Maleic anhydride (1 mole) in 150 ml. C6H6, cooled to 5°, 54 g. liquid (CH2:CH)2 added, and the mixture heated to 115° (within 15 min. the temperature rises to 145° and the pressure to 11 atm.) and allowed to stand overnight, gives 90% cis-Δ4-tetrahydrophthalic anhydride (I), m. 103-4°. I (30.4 g.) in 150 ml. AcOH, hydrogenated 0.5 hr. over 200 mg. Pt oxide at room temperature and 4.5 atm., and the mixture boiled with H2O, gives 90% cis-hexahydrophthalic acid, m. 190-1°.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Top Picks: new discover of 610-09-3

Compound(610-09-3)Category: benzisoxazole received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(cis-Cyclohexane-1,2-dicarboxylic acid), if you are interested, you can check out my other related articles.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Application of the cyano ester ring closure to five- and six-membered rings, published in 1938, which mentions a compound: 610-09-3, mainly applied to , Category: benzisoxazole.

cf. F. and Kao, C. A. 23, 2424. Et α,α’-dibromopimelate and KCN in absolute EtOH, refluxed for 60 hrs., give 80-8% of Et 1-cyano-1,2-cyclopentanedicarboxylate, b2 126-8°, d420 1.108, nD20 1.4560; hydrolysis with concentrated HCl gives a mixture of trans- and cis-1,2-cyclopentanedicarboxylic acid (Perkins, J. Chem. Soc. 65, 572(1894)). Similarly Et α,α’-dibromosuberate yields 48-55% of Et 1-cyano-1,2-cyclohexanedicarboxylate, b2 129-30°, d420 1.082, nD20 1.4570; hydrolysis with 20% HCl yields a mixture of the 2 1,2-cyclohexanedicarboxylic acids, the trans-isomer being obtained pure (Baeyer, Ann. 258, 213(1890)). Et α,α’-dibromoazelate and Et α,α’-dibromosebacate failed to give detectable quantities of the cyclic CN esters containing 7- or 8-membered rings.

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics