Category: 610-09-3

Product Details of 610-09-3. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about [Ni(cyclam)]2+ and [Ni(R,S-Me6cyclam)]2+ as Linkers or Counterions In Uranyl-Organic Species with cis- and trans-1,2-Cyclohexanedicarboxylate Ligands. Author is Thuery, Pierre; Harrowfield, Jack.

The macrocyclic species [Ni(cyclam)]2+ and [Ni(R,S-Me6cyclam)]2+ were used as addnl. cations in the solvo-hydrothermal synthesis of five uranyl ion complexes with cis- or trans-1,2-cyclohexanedicarboxylic acids (c-1,2-chdcH2 and t-1,2-chdcH2). In the complex [UO2(c-chdc)2Ni(cyclam)(H2O)] (1), dimeric uranyl dicarboxylate subunits are assembled into a two-dimensional (2D) network through axial coordination of NiII to carboxylate groups. Although they involve different isomers, the complexes [(UO2)2(c-chdc)2(c-chdcH)2Ni(cyclam)] (2) and [(UO2)2(t-chdc)2(t-chdcH)2Ni(cyclam)] (3) are very similar, both containing uranyl-based one-dimensional (1D) subunits which are assembled into 2D networks by bridging [Ni(cyclam)]2+ groups. The orientation of the uncoordinated carboxylic group is different in 2 and 3, the layers in 2 being hydrogen bonded to each other through carboxylic acid dimer formation. Using the pure (1R,2R) enantiomer of t-1,2-chdcH2 gives the complex [Ni(cyclam)][(UO2)5(R-t-chdc)3(R-t-chdcH)(O)2(CH3COO)] (4), in which pentanuclear uranyl subunits are assembled into 1D chains by dicarboxylic/-ate ligands in the usual bis(equatorial) chair conformation, another ligand in the divergent bis(axial) conformation uniting these chains into a 2D assembly; the [Ni(cyclam)]2+ ions are simple counterions and are stacked in parallel fashion between the layers. [Ni(R,S-Me6cyclam)][Ni(R,S-Me6cyclam)(H2O)2][(UO2)2(t-chdc)2(O)]2 (5), in which the (1R,2R) enantiomer of t-chdcH2 used has undergone racemization, contains discrete bis(μ3-oxo)-centered tetranuclear uranyl complexes, organized into columns and layers by extensive hydrogen bonding to the counterions. The discoidal shape, available axial coordination sites, and hydrogen bond donor potential of these macrocyclic NiII complexes make them efficient assembling agents in uranyl-organic coordination polymers. As often observed in the presence of d-block metal cations, uranyl luminescence is either completely or partially quenched in complexes 1 and 3, resp.

From this literature《[Ni(cyclam)]2+ and [Ni(R,S-Me6cyclam)]2+ as Linkers or Counterions In Uranyl-Organic Species with cis- and trans-1,2-Cyclohexanedicarboxylate Ligands》,we know some information about this compound(610-09-3)Product Details of 610-09-3, but this is not all information, there are many literatures related to this compound(610-09-3).

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Stereoisomeric biologically active compounds. I. Some conversions of cis-4-chloro-4-cyclohexene-1,2-dicarboxylic acid》. Authors are Rashidyan, L. G.; Tatevosyan, G. T..The article about the compound:cis-Cyclohexane-1,2-dicarboxylic acidcas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O).Safety of cis-Cyclohexane-1,2-dicarboxylic acid. Through the article, more information about this compound (cas:610-09-3) is conveyed.

cf. Baeyer, Ann. Chem. 258, 215(1890); U.S. 1,967,862, CA 28, 5994. To 10 g. cis-4-chloro-4-cyclohexene-1,2-dicarboxylic acid (I) and 60 ml. H2O, under cooling and stirring, a solution of 21 g. KMnO4 in 650 650 ml. H2O was added over 3 hrs. The cooling and stirring was another 2 hrs. and the mixture left standing overnight, yielding meso-butane-1,2,3,4-tetracarboxylic acid m. 191-2°. I (204.5 g.) and 15 ml. concentrated H2SO4 in 500 ml. absolute MeOH was refluxed for 8 hrs. Dimethyl cis-4-chloro-4-cyclohexene-1,2-dicarboxylate (II), b5 148-50°, d204 1.0553, n20D 1.4935 was obtained in 71.3% yield. II (20 g.) and 18 ml. 85% H2NNH2 was refluxed for 3 hrs. Trans-4-chloro-4-cyclohexene-1,2-dicarboxylic acid dihydrazide (III) m. 222-4° (60% EtOH) was obtained in 69.5% yield. To 30 g. III in 105 ml. 10% HCl and 280 ml. CH2Cl2 at 18-20°, a solution of 20.8 g. NaNO3 in 48.5 ml. H2O was slowly added. The nonaqueous layer was dried, filtered, and treated with 160 ml. absolute EtOH. The CH2Cl2 was evaporated, the mixture refluxed for 2 hrs., 210 ml. 40% NaOH added and steam distilled The distillate was acidified with 10% HCl giving the trans-4-chloro-1,2-diamino-4-cyclohexene-2HCl m. 326-8° in 72.1% yield. III (38 g.) and a solution of 26.6 g. NaOH in 350 ml. H2O was refluxed for 12 hrs. and acidified, giving trans-4-chloro-4-cyclohexene-1,2-dicarboxylic acid (IV) m. 115-17° (H2O) in 89.8% yield. IV (10 g.) was oxidized with KMnO4 as described above, giving the dianhydride of dl-butane-1,2,3,4-tetracarboxylic acid m. 172-3°. A solution of 21 g. IV, 8 g. NaOH and 70 ml. H2O was hydrogenated in an autoclave in the presence of 35 g. Ni on Cr2O3 at 100° and 100 atm. The solution was filtered and acidified giving trans-cyclohexane-1,2-dicarboxylic acid (V) m. 220° (Me2O) in 78.2% yield. I (60 g.) and 23.5 g. NaOH in 200 ml. H2O was hydrogenated as described above giving cis-cyclohexane-1,2-dicarboxylic acid (VI), m. 192°, in 92.1% yield. A mixture of 8 g. VI and 20 ml. concentrated HCl was heated in a sealed tube at 180° for 8-10 hrs. and V, m. 220-1°, was obtained in 88.8% yield.

From this literature《Stereoisomeric biologically active compounds. I. Some conversions of cis-4-chloro-4-cyclohexene-1,2-dicarboxylic acid》,we know some information about this compound(610-09-3)Safety of cis-Cyclohexane-1,2-dicarboxylic acid, but this is not all information, there are many literatures related to this compound(610-09-3).

Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Hexathydro-o-phthalic acids》. Authors are Vavon, G.; Peignier, P..The article about the compound:cis-Cyclohexane-1,2-dicarboxylic acidcas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O).COA of Formula: C8H12O4. Through the article, more information about this compound (cas:610-09-3) is conveyed.

Hydrogenation of mono-Me o-phthalate with Pt black as catalyst gives cis-hexahydrophthalate (I). The l-rotatory isomer of I (m. 148-9°, [α573 6.67°, c 0.1 in EtOH) gives on saponification an inactive acid. The l-rotatory cis-hexahydrophthalamide ([α]573 -15.4°, c 0.02 in EtOH), isolated by means of the quinine salt, gives on heating an inactive imide.

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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: cis-Cyclohexane-1,2-dicarboxylic acid( cas:610-09-3 ) is researched.Product Details of 610-09-3.Yang, Ying; Wu, Rui; Huang, Shaohua; Bai, Zhengwu published the article 《Silica sol assisted chromatographic NMR spectroscopy for resolution of trans- and cis-isomers》 about this compound( cas:610-09-3 ) in Journal of Magnetic Resonance. Keywords: silica soluble cisisomer transisomer chromatog NMR resolution; Chromatographic NMR spectroscopy; DOSY; Isomer; Resolution; Silica sol. Let’s learn more about this compound (cas:610-09-3).

Chromatog. NMR spectroscopy can seperate the mixtures of species with significantly different mol. size, but generally fails for isomeric species. Herein, we reported the resolution of trans- and cis-isomers and their structural analog, which are different in mol. shapes, but similar in mass, were greatly enhanced in the presence of silica soluble The mixtures of maleic acid, fumaric acid and succinic acid, and the mixtures of trans- and cis-1,2-cyclohexanedicarboxylic acids, were distinguished by virtue of their different degrees of interaction with silica soluble Moreover, we found mixed solvents could improve the spectral resolution of DOSY spectra of mixtures

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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Formula: C8H12O4. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about [Ni(cyclam)]2+ and [Ni(R,S-Me6cyclam)]2+ as Linkers or Counterions In Uranyl-Organic Species with cis- and trans-1,2-Cyclohexanedicarboxylate Ligands. Author is Thuery, Pierre; Harrowfield, Jack.

The macrocyclic species [Ni(cyclam)]2+ and [Ni(R,S-Me6cyclam)]2+ were used as addnl. cations in the solvo-hydrothermal synthesis of five uranyl ion complexes with cis- or trans-1,2-cyclohexanedicarboxylic acids (c-1,2-chdcH2 and t-1,2-chdcH2). In the complex [UO2(c-chdc)2Ni(cyclam)(H2O)] (1), dimeric uranyl dicarboxylate subunits are assembled into a two-dimensional (2D) network through axial coordination of NiII to carboxylate groups. Although they involve different isomers, the complexes [(UO2)2(c-chdc)2(c-chdcH)2Ni(cyclam)] (2) and [(UO2)2(t-chdc)2(t-chdcH)2Ni(cyclam)] (3) are very similar, both containing uranyl-based one-dimensional (1D) subunits which are assembled into 2D networks by bridging [Ni(cyclam)]2+ groups. The orientation of the uncoordinated carboxylic group is different in 2 and 3, the layers in 2 being hydrogen bonded to each other through carboxylic acid dimer formation. Using the pure (1R,2R) enantiomer of t-1,2-chdcH2 gives the complex [Ni(cyclam)][(UO2)5(R-t-chdc)3(R-t-chdcH)(O)2(CH3COO)] (4), in which pentanuclear uranyl subunits are assembled into 1D chains by dicarboxylic/-ate ligands in the usual bis(equatorial) chair conformation, another ligand in the divergent bis(axial) conformation uniting these chains into a 2D assembly; the [Ni(cyclam)]2+ ions are simple counterions and are stacked in parallel fashion between the layers. [Ni(R,S-Me6cyclam)][Ni(R,S-Me6cyclam)(H2O)2][(UO2)2(t-chdc)2(O)]2 (5), in which the (1R,2R) enantiomer of t-chdcH2 used has undergone racemization, contains discrete bis(μ3-oxo)-centered tetranuclear uranyl complexes, organized into columns and layers by extensive hydrogen bonding to the counterions. The discoidal shape, available axial coordination sites, and hydrogen bond donor potential of these macrocyclic NiII complexes make them efficient assembling agents in uranyl-organic coordination polymers. As often observed in the presence of d-block metal cations, uranyl luminescence is either completely or partially quenched in complexes 1 and 3, resp.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Structure of some cyclohexyl compounds as related to their ability to stimulate plant growth.Quality Control of cis-Cyclohexane-1,2-dicarboxylic acid.

Of 9 cyclohexyl compounds tested as plant growth regulators on bush bean plants (Phaseolus vulgaris), only cyclohexanecarboxylic (I) [98-89-5] and cyclohexylacetic acid (II) [5292-21-7] significantly increased pod production Among I, II, cyclohexylpropionic [701-97-3], and cyclohexylbutyric acid [4441-63-8], the stimulating effect decreased as the number of CH2 groups in the side chain increased, from 0-3. The effective compounds possessed an H-saturated C6-ring with a single carboxyl group attached directly to the ring or separated by 1 ≤ CH2 group.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Kolbe electrolyses of cis- and trans-methyl hydrogen hexahydrophthalate》. Authors are Overberger, C. G.; Kabasakalian, Peter.The article about the compound:cis-Cyclohexane-1,2-dicarboxylic acidcas:610-09-3,SMILESS:O=C([C@H]1[C@@H](C(O)=O)CCCC1)O).Application In Synthesis of cis-Cyclohexane-1,2-dicarboxylic acid. Through the article, more information about this compound (cas:610-09-3) is conveyed.

The Kolbe electrolysis of cis- and trans-Me H hexahydrophthalate (I) in anhydrous MeOH has been carried out. Identical mixtures of uncoupled products were obtained from both isomers. Me 1-cyclohexene- and 2-cyclohexene-1-carboxylate and Me cyclohexanecarboxylate were obtained as monomeric products. Dimeric materials were obtained for the first time from I. Saponification of the dimeric ester mixture gave 2 perhydrodiphenic acids, trans-anti-trans and trans-syn-trans, which were separated and identified quantitatively by adsorption chromatography and infrared analysis. Since epimerization occurred on all centers α to the carboxyl group, no conclusion about the stereochemistry of the radicals could be deduced from the ratios of coupled products.

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Safety of cis-Cyclohexane-1,2-dicarboxylic acid. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Stereochemistry of cyclic dicarboxylic acids studies by potentiometric titration. IV. Effect of the composition and dielectric constant of acetone-water solutions on the ionization constants of cis- and trans-1,2-dicarboxylic acids. Author is Salakhov, M. S.; Israfilov, A. I.; Shamilov, T. O..

Ionization constants of cis and trans isomers of 1,2-cyclohexanedicarboxylic acid, 4-cyclohexene-1,2-dicarboxylic acid, 1-methyl-4-cyclohexene-1,2-dicarboxylic acid, 5-norbornene-2,3-dicarboxylic acid, and 1,2,3,4,9,9-hexachloro-1,4,4a,5,6,7,8,8a-octahydro-1,4-methanonaphthalene-2,3-dicarboxylic acid, cis-3-methyl-4-cyclohexene-1,2-dicarboxylic acid, and cis-4,5-dimethyl-4-cyclohexene-1,2-dicarboxylic acid were determined and correlated with configuration and solvent composition

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Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about Platinum(II) and palladium(II) complexes analogous to oxaliplatin with different cyclohexyldicarboxylate isomeric anions and their in vitro antitumour activity. Structural elucidation of [Pt(C2O4)(cis-dach)].Product Details of 610-09-3.

Several new PtII and PdII complexes bearing the enantiomerically pure (1R,2R)-(-)-1,2-cyclohexanediamine (dach) ligand, [MX2{(1R,2R)-dach}], where M = Pt or Pd, X2 = cis- or trans- or (1R,2R)-1,2-cyclohexyldicarboxylate anions, were synthesized and characterized physicochem. and spectroscopically. These complexes were screened in vitro against the three tumor cell lines K562, HeLa and L929, and the results obtained were compared with those of the reference standards, cisplatin, carboplatin and oxaliplatin; the known antitumor drugs. The single crystal x-ray structure determination of the [Pt(C2O4)(cis-dach)] complex is discussed and compared with that of oxaliplatin, [Pt(C2O4){(1R,2R)-dach}].

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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics

COA of Formula: C8H12O4. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: cis-Cyclohexane-1,2-dicarboxylic acid, is researched, Molecular C8H12O4, CAS is 610-09-3, about An Open-Framework Material with Dangling Organic Functional Groups in 24-Ring Channels. Author is Zhu, Jin; Bu, Xianhui; Feng, Pingyun; Stucky, Galen D..

An open-framework material with dangling organic functional groups in 24-ring channels, Zn3(O3PCH2CO2)2(O3PCH2CO2H)(NH3CH2CH2NH3)(BTC) (BTC = 1,3,5-benzenetricarboxylic acid), was prepared and its crystal structure was determined The material with a tetrahedral zeolite-type structure belongs to space group R3̅, Z = 18, a 41.663(7), c 7.843(2)Å, R = 7.43, Rw = 19.7%. Each O3PCH2CO2 group behaves like a regular PO43- group in zeolite-type frameworks and is 4-connected to 4 Zn sites; 2 of the 3 unique Zn sites are 4-connected to P atoms sites. The 3rd Zn site is pentacoordinated to 5 O atoms and 3-connected to P sites because 2 pairs of O atoms are chelating O atoms from 2 O3PCH2CO2 groups.

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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics