Final Thoughts on Chemistry for 3326-71-4

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In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called DMF as Methine Source: Copper-Catalyzed Direct Annulation of Hydrazides to 1,3,4-Oxadiazoles, published in 2019, which mentions a compound: 3326-71-4, mainly applied to DMF aryl hydrazide copper catalyst oxidative heterocyclization green chem; aryl oxadiazole preparation oxygen copper catalyst oxidation green chem; oxadiazolone aryl preparation, Product Details of 3326-71-4.

An unprecedented Cu-catalyzed direct annulation of hydrazides with N,N-dimethylformamide (DMF) was developed, providing an efficient synthesis of valuable 1,3,4-oxadiazoles. This process featured short reaction time and safely conducted on gram scale. The reaction also facilitated the convenient synthesis of 1,3,4-oxadiazole-2(3H)-ones. Moreover, the mechanistic studies suggested that the source of CH was from the N-Me group of DMF.

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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics