In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis, antimicrobial and antioxidant evaluation, and molecular docking study of 4,5-disubstituted 1,2,4-triazole-3-thiones, published in 2020-09-05, which mentions a compound: 3326-71-4, Name is 2-Furoic hydrazide, Molecular C5H6N2O2, Category: benzisoxazole.
In order to develop potential antimicrobial agents, some 1,2,4-triazole-3-thiones I (R = Et, Ph, 4-nitrophenyl, etc.; Ar = Ph, furan-2-yl, pyridin-4-yl, etc.) were synthesized from the reaction of hydrazides ArC(O)NHNH2 with isothiocyanates RN=C=S under optimized conditions in deep eutectic solvent of potassium carbonate-glycerol (1:5 M ratio). Blocking properties of all products were assessed on a variety of Gram-pos. and Gram-neg. bacterial as well as fungal pathogens. Good to excellent inhibitory effects especially against fungi were observed with all synthesized compounds Compound I (R = 4-nitrophenyl; Ar = 4-hydroxyphenyl) showed significant antioxidant activity according to the results obtained from 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging experiments The possible interaction mechanism of synthetic triazoles with 1IYL enzyme on Aspergillus fumigatus was investigated by mol. docking method. A complete agreement was found between exptl. data and theor. calculations Hydrogen bond acceptor strength of N-1 in 1,2,4-triazole rings was the main cause of the observed differences.
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Reference:
Benzisoxazole – Wikipedia,
Benzisoxazole – an overview | ScienceDirect Topics