New Advances in Chemical Research in 2021. Irreversible inhibitors are therefore the equivalent of poisons in heterogeneous catalysis. 127-17-3, Name is 2-Oxopropanoic acid, molecular formula is C3H4O3, Computed Properties of https://www.ambeed.com/products/127-17-3.html, belongs to benzisoxazole compound, is a common compound. In a patnet, author is HRIB, NJ, once mentioned the new application about 127-17-3.
A series of benzisoxazole- and benzisothiazole-3-carboxamides has been prepared and tested for potential antipsychotic activity. In general, the compounds showed an affinity for dopamine D-2 and serotonin 5HT(2A) and 5HT(1A) receptors. Several Members of this series have demonstrated activity in animal models predictive of potential antipsychotic activity. In addition, compounds 18, 19, 22, 27, 28, 43, and 44 have also shown a potential for reduced EPS liability as suggested by the ratio of activity seen in mesolimbic-mediated vs nigrostriatal-mediated behavioral assays.
You can get involved in discussing the latest developments in this exciting area about 127-17-3, Computed Properties of https://www.ambeed.com/products/127-17-3.html.
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics