New discoveries in chemical research and development in 2021.Quality Control of 3-Hydroxy-3-methylbutanoic acid, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction. 625-08-1, Name is 3-Hydroxy-3-methylbutanoic acid, molecular formula is C5H10O3. In an article, author is Guo, Sheng,once mentioned of 625-08-1.
A mild and practical method for the catalytic installation of the amino group across alkenes and alkynes has long been recognized as a significant challenge in synthetic chemistry. As the direct hydroamination of olefins using ammonia requires harsh conditions, the development of suitable electrophilic aminating reagents for formal hydroamination methods is of importance. Herein, we describe the use of 1,2-benzisoxazole as a practical electrophilic primary amine source. Using this heterocycle as a new amino group delivery agent, a mild and general protocol for the copper-hydride-catalyzed hydroamination of alkenes and alkynes to form primary amines was developed. This method provides access to a broad range of chiral alpha-branched primary amines and linear primary amines, as demonstrated by the efficient synthesis of the antiretroviral drug maraviroc and the formal synthesis of several other pharmaceutical agents.
Quality Control of 3-Hydroxy-3-methylbutanoic acid, In the meantime we’ve collected together some recent articles in this area about 625-08-1 to whet your appetite. Happy reading!
Reference:
Benzisoxazole – Wikipedia,
,Benzisoxazole – an overview | ScienceDirect Topics